Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14204990 | 0.92 | SETDB1 (0.59) | SETDB1MTNR1ANPSR1HPGDKMT2A | |
| SCHEMBL10781973 | 0.86 | SETDB1 (0.51) | SETDB1MTNR1ANPSR1HPGDLMNA | |
| SCHEMBL14651452 | 0.86 | SETDB1 (0.54) | SETDB1MTNR1ANPSR1HPGDKMT2A | |
| SCHEMBL14067342 | 0.83 | SETDB1 (0.49) | SETDB1MTNR1ANPSR1HPGDL3MBTL1 | |
| SCHEMBL13579194 | 0.83 | CYP3A4 (0.50) | SETDB1MTNR1ANPSR1HPGDLMNA | |
| SCHEMBL17123628 | 0.82 | SETDB1 (0.51) | SETDB1MTNR1ANPSR1HPGDKMT2A | |
| SCHEMBL1799028 | 0.82 | SETDB1 (0.51) | SETDB1MTNR1ANPSR1HPGDKMT2A | |
| SCHEMBL15030741 | 0.82 | SETDB1 (0.51) | SETDB1MTNR1ANPSR1HPGDKMT2A | |
| SCHEMBL5988458 | 0.82 | MTNR1A (0.65) | MTNR1ALMNAKMT2AMTNR1BNQO2 | |
| SCHEMBL9861860 | 0.82 | SETDB1 (0.51) | SETDB1MTNR1ANPSR1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |