SCHEMBL14067384

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14067385	0.85	NPC1 (0.44)	APPNPC1RAB9AALDH1A1NFKB1
	SCHEMBL14067374	0.79	APP (0.40)	APPNPC1RAB9AGAAMAP3K11
	SCHEMBL14067366	0.78	APP (0.67)	APPNPC1RAB9AALDH1A1KDM4E
	SCHEMBL14067382	0.78	APP (0.43)	APPNPC1RAB9AALDH1A1KDM4E
	SCHEMBL14067394	0.76	APP (0.43)	APPNPC1RAB9AALDH1A1NFKB1
	SCHEMBL14067370	0.76	TLR9 (0.47)	APPNPC1RAB9AALDH1A1GAA
	SCHEMBL14067397	0.75	APP (0.40)	APP
	SCHEMBL14067381	0.75	APP (0.43)	APPNPC1RAB9AALDH1A1KDM4E
	SCHEMBL14067376	0.74	APP (0.39)	APPNPC1RAB9AGAACRHR1
	SCHEMBL14067400	0.73	APP (0.41)	APPNPC1RAB9AGAAMAP3K11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.