Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.42 |
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067400 | 0.86 | APP (0.41) | APPSYKPLK4JAK2RET | |
| SCHEMBL14067368 | 0.84 | TLR9 (0.48) | APPSYKMAPTHPGDTLR9 | |
| SCHEMBL14067381 | 0.82 | APP (0.43) | APPMAPTTLR9NPC1RAB9A | |
| SCHEMBL14067364 | 0.80 | APP (0.67) | APPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14067370 | 0.78 | TLR9 (0.47) | APPSYKMAPTHPGDTLR9 | |
| SCHEMBL14067382 | 0.77 | APP (0.43) | APPSYKTLR9TLR7NPC1 | |
| SCHEMBL14067403 | 0.76 | APP (0.44) | APPSYKMAPTHPGDTLR9 | |
| SCHEMBL3431380 | 0.75 | APP (0.67) | APPHPGDNPC1POLBRAB9A | |
| SCHEMBL3302541 | 0.75 | APP (0.49) | APPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14067565 | 0.75 | APP (0.45) | APPSYKJAK2RETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080219922-A1 | Alzheimer's Disease Imaging Agents | EMORY UNIVERSITY | 2008-09-11 | — | — | US | disclosed |
| US-20080219922-A1 | Alzheimer's Disease Imaging Agents | EMORY UNIVERSITY | 2008-09-11 | — | — | US | disclosed |
| WO-2007033080-A2 | ALZHEIMER'S DISEASE IMAGING AGENTS | EMORY UNIVERSITY (US) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080219922-A1 | Alzheimer's Disease Imaging Agents | APP, PSEN1, MAPT | APP 1/4885SYK 3020/4885PLK4 3929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.