Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.53 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067947 | 0.89 | GRIN2B (0.52) | PTGDR2AKR1B10AKR1B1PTGER2PTGDR | |
| SCHEMBL14067946 | 0.83 | HTR6 (0.61) | PTGDR2PTGER2PTGDRCYP2C9GRIN2B | |
| SCHEMBL4132976 | 0.82 | HRH1 (0.56) | PTGDR2GRIN2B | |
| SCHEMBL14067659 | 0.82 | HTR6 (0.52) | GRIN2B | |
| SCHEMBL14067986 | 0.82 | GRIN2B (0.56) | PTGDR2GRIN2B | |
| SCHEMBL14067648 | 0.82 | GRIN2B (0.49) | PTGDR2AKR1B10AKR1B1PTGDRGRIN2B | |
| SCHEMBL14067655 | 0.81 | PTGDR2 (0.53) | PTGDR2AKR1B10AKR1B1PTGER2PTGDR | |
| SCHEMBL14067779 | 0.81 | HTR6 (0.60) | PTGDR2AKR1B10AKR1B1 | |
| SCHEMBL3724842 | 0.81 | HTR6 (0.62) | GRIN2B | |
| SCHEMBL14067977 | 0.79 | GRIN2B (0.51) | PTGDR2GRIN2BBAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115098-A2 | SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLES, METHODS FOR THE PRODUCTION AND THE USE THEREOF | ALLA CHEM, LLC (US) | 2008-09-25 | — | — | WO | disclosed |