Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 11/20 | 0.56 |
| ▸ | HTR6 | P50406 | 11/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067986 | 0.91 | GRIN2B (0.56) | HRH1HTR6GRIN2BCNR1HDAC1 | |
| SCHEMBL14067977 | 0.90 | GRIN2B (0.51) | HRH1HTR6GRIN2BHDAC1HDAC6 | |
| SCHEMBL14067785 | 0.90 | HRH1 (0.59) | HRH1HTR6GRIN2B | |
| SCHEMBL14067988 | 0.88 | GRIN2B (0.51) | HRH1HTR6GRIN2BHDAC1HDAC6 | |
| SCHEMBL14067659 | 0.87 | HTR6 (0.52) | HRH1HTR6GRIN2BHDAC1HDAC6 | |
| SCHEMBL14067987 | 0.85 | HDAC1 (0.56) | HRH1HTR6CNR1HDAC1HDAC6 | |
| SCHEMBL14067794 | 0.85 | HRH1 (0.62) | HRH1HTR6GRIN2B | |
| SCHEMBL14067941 | 0.85 | HRH1 (0.66) | HRH1HTR6GRIN2B | |
| SCHEMBL14067975 | 0.85 | GRIN2B (0.53) | HRH1HTR6GRIN2B | |
| SCHEMBL14067947 | 0.84 | GRIN2B (0.52) | HRH1HTR6GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115098-A2 | SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLES, METHODS FOR THE PRODUCTION AND THE USE THEREOF | ALLA CHEM, LLC (US) | 2008-09-25 | — | — | WO | disclosed |