Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 19/20 | 0.60 |
| ▸ | PRKDC | P78527 | 4/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11984740 | 0.79 | GSK3B (0.57) | ATRPRKDCPRKCAGSK3BPRKCQ | |
| SCHEMBL8307717 | 0.77 | ATR (0.69) | ATRPRKDCATM | |
| SCHEMBL2484387 | 0.76 | ATR (1.00) | ATRPRKDCATM | |
| SCHEMBL3460862 | 0.71 | ATR (0.72) | ATRPRKDCATMPRKCAGSK3B | |
| SCHEMBL19101079 | 0.70 | ATR (0.84) | ATRPRKDCPRKCAGSK3BPRKCQ | |
| SCHEMBL11907360 | 0.69 | ATR (0.70) | ATRPRKDCATMPRKCAGSK3B | |
| SCHEMBL11984659 | 0.69 | GSK3B (0.65) | ATRPRKDCPRKCAGSK3BPRKCQ | |
| SCHEMBL11984739 | 0.69 | PRKCQ (0.78) | ATRPRKDCPRKCAGSK3BPRKCQ | |
| SCHEMBL11984736 | 0.68 | GSK3B (0.82) | ATRPRKDCPRKCAGSK3BPRKCQ | |
| SCHEMBL3060457 | 0.68 | ATR (0.71) | ATRPRKDCATMGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008106692-A1 | PIM KINASE INHIBITORS AND METHODS OF THEIR USE | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |