Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.48 |
| ▸ | HRH1 | P35367 | 4/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067838 | 0.91 | GRIN2B (0.49) | HTR6HRH1PTGDR2GRIN2BPTGDR | |
| SCHEMBL14067989 | 0.91 | HTR6 (0.50) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL14067978 | 0.91 | KDM4E (0.48) | HTR6PTGDR2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL14067835 | 0.86 | HTR6 (0.47) | HTR6HRH1PTGDR2GRIN2B | |
| SCHEMBL10127773 | 0.86 | HSD17B10 (0.52) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL14067981 | 0.84 | TBXA2R (0.50) | PTGDR2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3318769 | 0.83 | HTR6 (0.62) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL14067949 | 0.81 | BAZ2B (0.52) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL8034825 | 0.81 | HTR6 (0.69) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL14067648 | 0.80 | GRIN2B (0.49) | HTR6HRH1ADRA2AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115098-A2 | SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLES, METHODS FOR THE PRODUCTION AND THE USE THEREOF | ALLA CHEM, LLC (US) | 2008-09-25 | — | — | WO | disclosed |