Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.43 |
| ▸ | RXRB | P28702 | 8/20 | 0.43 |
| ▸ | RXRG | P48443 | 6/20 | 0.43 |
| ▸ | RARB | P10826 | 8/20 | 0.43 |
| ▸ | RARG | P13631 | 7/20 | 0.43 |
| ▸ | RARA | P10276 | 6/20 | 0.43 |
| ▸ | HNF4A | P41235 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1406668 | 0.89 | RXRA (0.41) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL1406423 | 0.76 | RARB (0.48) | RXRARARBRARGRARA | |
| SCHEMBL1406424 | 0.76 | RARB (0.48) | RXRARARBRARGRARA | |
| SCHEMBL5047887 | 0.74 | RARB (0.60) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL1406780 | 0.74 | RARB (0.62) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL1406779 | 0.74 | RARB (0.62) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL1406590 | 0.72 | RARB (0.46) | RXRARXRBRARBRARGRARA | |
| SCHEMBL5047666 | 0.71 | RARB (0.64) | RXRARXRBRARBRARGRARA | |
| SCHEMBL10339717 | 0.69 | RXRA (0.58) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL10339718 | 0.69 | RXRA (0.58) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513793-B1 | NOVEL LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2011-03-09 | — | — | EP | claimed |