Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.46 |
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | FABP7 | O15540 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475058 | 0.98 | FABP7 (0.49) | CES2CES1FABP7FABP5MEN1 | |
| SCHEMBL6649308 | 0.92 | CES2 (0.50) | CES2CES1MEN1KMT2ACHRNA7 | |
| SCHEMBL3671553 | 0.92 | CES2 (0.50) | CES2CES1MEN1KMT2ACHRNA7 | |
| SCHEMBL1926317 | 0.81 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2CHRNA7LMNA | |
| SCHEMBL1994114 | 0.81 | FABP7 (0.47) | FABP7FABP5MEN1KMT2AFAAH | |
| SCHEMBL28747257 | 0.81 | FABP7 (0.47) | FABP7FABP5MEN1KMT2AFAAH | |
| SCHEMBL6649622 | 0.80 | MAPT (0.43) | CES2CES1MEN1KMT2ACHRNA7 | |
| SCHEMBL13531404 | 0.80 | CYP19A1 (0.42) | KMT2ASMN1; SMN2LMNAALDH1A1RAB9A | |
| SCHEMBL14720174 | 0.79 | MEN1 (0.63) | FABP7FABP5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL60478 | 0.79 | MEN1 (0.63) | FABP7FABP5MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149835-B | Preparation method for rapidly generating alpha-ketoester by iodine-mediated oxidation of alpha-diazo ester | 广西师范大学 | 2023-05-02 | — | — | CN | disclosed |
| US-8846954-B2 | Crystallisation and purification of glycopyrronium bromide | SOSEI R&D LTD. (GB) | 2014-09-30 | — | — | US | disclosed |
| US-8846954-B2 | Crystallisation and purification of glycopyrronium bromide | SOSEI R&D LTD. (GB) | 2014-09-30 | — | — | US | disclosed |
| US-20080227988-A1 | Reaction of glycopyrronium base with methyl bromide in solvent selected such that diastereoisomeric ratio of product favors R, S and S, R diastereoisomers over R, R, and S, S diastereoisomers, and separating desired diastereoisomers by controlled crystallisation steps; narrow particle size distribution | HEPTARES THERAPEUTICS LIMITED (GB) | 2008-09-18 | — | — | US | disclosed |
| US-20080227988-A1 | Reaction of glycopyrronium base with methyl bromide in solvent selected such that diastereoisomeric ratio of product favors R, S and S, R diastereoisomers over R, R, and S, S diastereoisomers, and separating desired diastereoisomers by controlled crystallisation steps; narrow particle size distribution | HEPTARES THERAPEUTICS LIMITED (GB) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227988-A1 | Reaction of glycopyrronium base with methyl bromide in solvent selected such that diastereoisomeric ratio of product favors R, S and S, R diastereoisomers over R, R, and S, S diastereoisomers, and separating desired diastereoisomers by controlled crystallisation steps; narrow particle size distribution | TSHR, GYPA, GLRB | CES2 3509/4885CES1 2567/4885FABP7 4642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.