Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637407 | 0.94 | KMT2A (0.56) | KMT2AL3MBTL1DRD2KDM1AMAOB | |
| SCHEMBL6637274 | 0.94 | KMT2A (0.56) | KMT2AL3MBTL1DRD2KDM1AMAOB | |
| SCHEMBL4929443 | 0.86 | ALDH1A1 (0.62) | KMT2AL3MBTL1DRD2KDM1AMAOB | |
| SCHEMBL2291956 | 0.86 | ALDH1A1 (0.62) | KMT2AL3MBTL1DRD2KDM1AMAOB | |
| SCHEMBL4929457 | 0.86 | ALDH1A1 (0.62) | KMT2AL3MBTL1DRD2KDM1AMAOB | |
| SCHEMBL14010470 | 0.86 | ALDH1A1 (0.62) | KMT2AL3MBTL1DRD2KDM1AMAOB | |
| SCHEMBL6642475 | 0.86 | KMT2A (0.52) | KMT2AL3MBTL1DRD2KDM1AMAOB | |
| SCHEMBL6642481 | 0.86 | KMT2A (0.52) | KMT2AL3MBTL1DRD2KDM1AMAOB | |
| SCHEMBL31333314 | 0.84 | ALDH1A1 (0.60) | KMT2AL3MBTL1DRD2KDM1AMAOB | |
| SCHEMBL21089801 | 0.83 | KMT2A (0.59) | KMT2AL3MBTL1DRD2KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109238-A1 | SUBSTITUTED CYCLOPENTYL PIPERIDINE CCR2 ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-09-12 | — | — | WO | disclosed |