Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 5/20 | 0.56 |
| ▸ | GNB1 | P62873 | 5/20 | 0.56 |
| ▸ | P2RY4 | P51582 | 8/20 | 0.52 |
| ▸ | P2RY12 | Q9H244 | 8/20 | 0.52 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.52 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.52 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ENTPD1 | P49961 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2609744 | 0.85 | PHLPP2 (0.53) | GNG2GNB1P2RY4P2RY12P2RY2 | |
| SCHEMBL29357302 | 0.79 | GNG2 (0.85) | GNG2GNB1P2RY4P2RY12P2RY2 | |
| SCHEMBL791019 | 0.79 | GNG2 (0.85) | GNG2GNB1P2RY4P2RY12P2RY2 | |
| SCHEMBL790823 | 0.78 | GNG2 (0.83) | GNG2GNB1P2RY4P2RY12P2RY2 | |
| SCHEMBL13213975 | 0.77 | GNG2 (0.86) | GNG2GNB1P2RY4P2RY12P2RY2 | |
| SCHEMBL13021512 | 0.75 | GNG2 (0.92) | GNG2GNB1P2RY4P2RY12P2RY2 | |
| SCHEMBL8945502 | 0.75 | P2RY4 (0.62) | GNG2GNB1P2RY4P2RY12P2RY2 | |
| SCHEMBL373494 | 0.74 | GNG2 (0.77) | GNG2GNB1P2RY4P2RY12P2RY2 | |
| SCHEMBL30382062 | 0.74 | GNG2 (0.77) | GNG2GNB1P2RY4P2RY12P2RY2 | |
| SCHEMBL3364421 | 0.74 | GNG2 (0.56) | GNG2GNB1P2RY4P2RY12P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107211-A2 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN (DE) | 2008-09-12 | — | — | WO | disclosed |