Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.43 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.43 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12205466 | 0.92 | MEN1 (0.41) | MEN1CYP2C19KMT2AALDH1A1KCNA4 | |
| SCHEMBL744431 | 0.85 | MEN1 (0.62) | MEN1CYP2C19KMT2AALDH1A1KCNA4 | |
| SCHEMBL12205336 | 0.82 | MAPK1 (0.41) | MEN1CYP2C19KMT2AALDH1A1MAPT | |
| SCHEMBL12205478 | 0.82 | NOS3 (0.36) | ALDH1A1MAPTMAPK1APAF1POLB | |
| SCHEMBL4812907 | 0.80 | MEN1 (0.55) | MEN1CYP2C19KMT2AALDH1A1KCNA4 | |
| SCHEMBL10085150 | 0.78 | MEN1 (0.53) | MEN1CYP2C19KMT2AALDH1A1KCNA4 | |
| SCHEMBL12163518 | 0.78 | SLC6A4 (0.38) | ALDH1A1TDP1MAPTMAPK1KDM1A | |
| SCHEMBL1301510 | 0.76 | MEN1 (0.50) | MEN1CYP2C19KMT2AALDH1A1KCNA4 | |
| SCHEMBL14491585 | 0.76 | MEN1 (0.47) | MEN1CYP2C19KMT2AALDH1A1KCNA4 | |
| SCHEMBL12163478 | 0.76 | TDP1 (0.33) | CYP2C19TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008106640-A1 | ANTIOXIDANT POLYMERS CONTAINING [1,2]-DITHIOLANE MOIETIES AND USES THEREOF | CEDARS-SINAI MEDICAL CENTER (US) | 2008-09-04 | — | — | WO | disclosed |