Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14029897 | 0.85 | HPGD (0.46) | GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL22672935 | 0.78 | GAA (0.62) | GAAMAPTF2KDM4EALDH1A1 | |
| SCHEMBL22673172 | 0.76 | GAA (0.48) | GAAMAPTALDH1A1 | |
| SCHEMBL14070689 | 0.71 | NAMPT (0.52) | L3MBTL1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL26398036 | 0.70 | GAA (0.51) | GAAMAPTMASP2F2ALDH1A1 | |
| SCHEMBL19476512 | 0.69 | GAA (0.60) | GAAMAPTL3MBTL1MASP2F2 | |
| SCHEMBL19476118 | 0.69 | GAA (0.60) | GAAMAPTL3MBTL1MASP2F2 | |
| SCHEMBL14005168 | 0.68 | NPC1 (0.50) | GAAKDM4EALDH1A1 | |
| SCHEMBL3989086 | 0.67 | GAA (0.65) | GAAMAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL13610792 | 0.67 | GAA (0.65) | GAAMAPTMASP2F2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112156-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |