Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | MELK | Q14680 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14071486 | 0.82 | KDM4E (0.38) | NAMPTALDH1A1MAPK1RAB9AITGB3 | |
| SCHEMBL14070689 | 0.77 | NAMPT (0.52) | NAMPTALDH1A1LMNANPC1POLB | |
| SCHEMBL166484 | 0.66 | LMNA (0.82) | ALDH1A1LMNANPC1POLBRAB9A | |
| SCHEMBL21768049 | 0.65 | LMNA (0.76) | NAMPTALDH1A1LMNANPC1POLB | |
| SCHEMBL14073993 | 0.65 | GAA (0.61) | HPGD | |
| SCHEMBL20525051 | 0.65 | LMNA (0.67) | NAMPTALDH1A1LMNANPC1POLB | |
| Hydrochloric Acid SCHEMBL27843329 | 0.65 | LMNA (0.80) | ALDH1A1LMNANPC1POLBRAB9A | |
| SCHEMBL18031536 | 0.64 | LMNA (0.74) | NAMPTALDH1A1LMNANPC1POLB | |
| SCHEMBL11626590 | 0.64 | POLB (0.74) | ALDH1A1LMNANPC1POLBRAB9A | |
| SCHEMBL4999846 | 0.64 | GAA (0.59) | POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112156-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |