Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 19/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13294093 | 1.00 | HSD11B1 (0.56) | HSD11B1 | |
| SCHEMBL1407052 | 1.00 | HSD11B1 (0.56) | HSD11B1 | |
| SCHEMBL13293982 | 0.90 | HSD11B1 (0.59) | HSD11B1 | |
| SCHEMBL13293983 | 0.90 | HSD11B1 (0.59) | HSD11B1 | |
| SCHEMBL14412986 | 0.86 | HSD11B1 (0.42) | HSD11B1 | |
| SCHEMBL16908775 | 0.84 | HSD11B1 (0.43) | HSD11B1 | |
| SCHEMBL4718475 | 0.83 | HSD11B1 (0.40) | HSD11B1 | |
| SCHEMBL1406716 | 0.81 | HSD11B1 (0.60) | HSD11B1 | |
| SCHEMBL13294070 | 0.81 | HSD11B1 (0.60) | HSD11B1 | |
| SCHEMBL13294007 | 0.80 | HSD11B1 (0.48) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295411-A1 | Pyrazoles as 11-beta-hsd-1 | F. Hoffmann-La Roche AG (CH) | 2011-03-16 | — | — | EP | disclosed |