Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14070858 | 0.88 | CNR1 (0.34) | AADAT | |
| SCHEMBL10044734 | 0.79 | AADAT (0.45) | AADAT | |
| SCHEMBL13060168 | 0.76 | AADAT (0.36) | AADAT | |
| SCHEMBL10044624 | 0.72 | GUCY1B2 (0.40) | AADAT | |
| SCHEMBL10044617 | 0.72 | F2 (0.41) | AADAT | |
| SCHEMBL10044597 | 0.72 | F2 (0.41) | AADAT | |
| SCHEMBL10044611 | 0.72 | GUCY1B2 (0.40) | AADAT | |
| SCHEMBL2630352 | 0.71 | JAK3 (0.55) | — | |
| SCHEMBL2630353 | 0.71 | JAK3 (0.55) | — | |
| SCHEMBL13305968 | 0.70 | GUCY1B2 (0.40) | AADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116139-A2 | N-HETEROCYCLIC COMPOUNDS USEFUL AS INHIBITORS OF JANUS KINASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-09-25 | — | — | WO | disclosed |