SCHEMBL14070937

SCHEMBL14070937

Cc1ccc2c(c1)OC(C1CCCCC1)CC2

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
STS P08842 2/20 0.48
CHRNA7 P36544 2/20 0.46
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14079476 0.97 STS (0.46) STSCHRNA7ESR1ESR2CYP1A2
SCHEMBL14070908 0.81 STS (0.48) STSCHRNA7ESR1ESR2
SCHEMBL12556702 0.79 CHRNA7 (0.42) CHRNA7ESR1ESR2HPGDKMT2A
SCHEMBL12556446 0.79 CHRNA7 (0.42) CHRNA7ESR1ESR2HPGDKMT2A
SCHEMBL14070963 0.79 STS (0.46) STSCHRNA7ESR1ESR2
SCHEMBL14070947 0.78 STS (0.45) STSCHRNA7ESR1ESR2
SCHEMBL14079590 0.78 STS (0.45) STSCHRNA7ESR1ESR2
SCHEMBL14070936 0.78 STS (0.45) STSCHRNA7
SCHEMBL14079683 0.76 STS (0.46) STSCHRNA7ESR1ESR2HPGD
SCHEMBL14070932 0.76 STS (0.52) STSCHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7429411-B2 Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition CHISSO PETROCHEMICAL CORPORATION (JP) 2008-09-30 US disclosed