SCHEMBL14070908

SCHEMBL14070908

Fc1ccc2c(c1)OC(C1CCCCC1)CC2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.48
CHRNA7 P36544 2/20 0.43
AKR1B1 P15121 2/20 0.37
FFAR1 O14842 1/20 0.37
HTR2A P28223 2/20 0.36
HTR2C P28335 2/20 0.36
MLNR O43193 1/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD2 P14416 1/20 0.35
KCNE1 P15382 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
CNR1 P21554 1/20 0.35
SLC6A2 P23975 1/20 0.35
NPY1R P25929 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14070963 0.97 STS (0.46) STSCHRNA7AKR1B1FFAR1HTR2A
SCHEMBL14070987 0.88 STS (0.39) STSCHRNA7AKR1B1FFAR1HTR2A
SCHEMBL14070994 0.88 STS (0.39) STSCHRNA7AKR1B1FFAR1HTR2A
SCHEMBL14071024 0.86 STS (0.38) STSCHRNA7AKR1B1FFAR1HTR2A
SCHEMBL14070995 0.83 STS (0.41) STSCHRNA7AKR1B1FFAR1HTR2A
SCHEMBL14070937 0.81 STS (0.48) STSCHRNA7ESR1ESR2
SCHEMBL14079590 0.81 STS (0.45) STSCHRNA7HTR1AESR1ESR2
SCHEMBL14070936 0.81 STS (0.45) STSCHRNA7FFAR1HTR2AHTR2C
SCHEMBL14070947 0.81 STS (0.45) STSCHRNA7FFAR1SLC6A2SLC6A4
SCHEMBL4944926 0.79 HTR1D (0.38) STSCHRNA7AKR1B1FFAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7429411-B2 Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition CHISSO PETROCHEMICAL CORPORATION (JP) 2008-09-30 US disclosed
US-7429411-B2 Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition CHISSO PETROCHEMICAL CORPORATION (JP) 2008-09-30 US disclosed