Ethylene Glycol

Ethylene Glycol

SCHEMBL1407202

C=CCOC(=O)O.OCCO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.42
TSHR P16473 4/20 0.39
MAPT P10636 3/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
PKM P14618 1/20 0.36
NPSR1 Q6W5P4 1/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
SNCA P37840 1/20 0.33
APP P05067 1/20 0.33
MAPK1 P28482 3/20 0.31
TP53 P04637 1/20 0.31
HIF1A Q16665 1/20 0.31
GAA P10253 2/20 0.31
RHOA P61586 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL1798352 1.00 CYP3A4 (0.42) CYP3A4TSHRMAPTCACNA1BAPBA1
Ethylene Glycol SCHEMBL7634094 1.00 CYP3A4 (0.42) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL7631790 0.92 CYP3A4 (0.43) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL9929 0.92
1,4-Butanediol SCHEMBL28304701 0.91 TSHR (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL744340 0.90
Methane SCHEMBL11128169 0.90
SCHEMBL175470 0.90
Ammonia Solution, Strong SCHEMBL438668 0.90
Hydrochloric Acid SCHEMBL9501363 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3318920-B1 NEAR INFRARED LIGHT-CUTTING OPTICAL ARTICLES WITH LOW RESIDUAL COLOR ESSILOR INT (FR) 2022-07-06 EP claimed
CN-109844620-B Near infrared light cut-off optical article with low residual color 依视路国际公司 2021-11-30 CN claimed
US-11124599-B2 Near infrared light-cutting optical articles with low residual color ESSILOR INTERNATIONAL (FR) 2021-09-21 US claimed
CN-108603946-B Blue light blocking optical materials comprising benzotriazole UV absorbers 依视路国际公司 2021-07-27 CN claimed
EP-3203271-B1 BLUE LIGHT CUTTING OPTICAL MATERIAL COMPRISING A BENZOTRIAZOLE UV ABSORBER ESSILOR INT (FR) 2021-01-27 EP claimed
US-20200262967-A1 NEAR INFRARED LIGHT-CUTTING OPTICAL ARTICLES WITH LOW RESIDUAL COLOR ESSILOR INTERNATIONAL (FR) 2020-08-20 US claimed
US-10308618-B2 Blue light cutting optical material comprising a benzotriazole UV absorber ESSILOR INTERNATIONAL (FR) 2019-06-04 US claimed
US-20190047967-A1 BLUE LIGHT CUTTING OPTICAL MATERIAL COMPRISING A BENZOTRIAZOLE UV ABSORBER ESSILOR INTERNATIONAL (FR) 2019-02-14 US claimed
EP-3318920-A1 NEAR INFRARED LIGHT-CUTTING OPTICAL ARTICLES WITH LOW RESIDUAL COLOR Essilor International (FR) 2018-05-09 EP claimed
WO-2017137372-A1 BLUE LIGHT CUTTING OPTICAL MATERIAL COMPRISING A BENZOTRIAZOLE UV ABSORBER Essilor International (Compagnie Générale d'Optique) (FR) 2017-08-17 WO claimed
EP-2317349-A1 Photochromic article TRANSITIONS OPTICAL, INC. (US) 2011-05-04 EP claimed
EP-1561130-B1 PHOTOCHROMIC ARTICLE TRANSITIONS OPTICAL INC (US) 2011-03-09 EP claimed
US-7465414-B2 Photochromic article TRANSITIONS OPTICAL, INC. (US) 2008-12-16 US claimed
EP-1561130-A1 PHOTOCHROMIC ARTICLE TRANSITIONS OPTICAL, INC. (US) 2005-08-10 EP claimed
WO-2004044626-A1 PHOTOCHROMIC ARTICLE TRANSITIONS OPTICAL, INC. (US) 2004-05-27 WO claimed
US-20040096666-A1 Photochromic article TRANSITIONS OPTICAL LIMITED (IE) 2004-05-20 US claimed
CN-1094829-C Coating composition, method for coating plastic substrate with the same and optically transparent plastic lens LEWIS WILLIAMS (US) 2002-11-27 CN claimed
US-6236797-B1 Light transmitting tube BRIDGESTONE CORPORATION (JP) 2001-05-22 US claimed
US-5286419-A Drying polarized film, testing for delamination, shaping, curving, filling lens mold with resin, curing BMC INDUSTRIES, INC. (US) 1994-02-15 US claimed
US-4069168-A AS PHOTOCHROMIC AGENT AND INFRARED ABSORBER; MONOMER OR POLYMER OF ALLYL GLYCOL CARBONATES PPG INDUSTRIES, INC. (US) 1978-01-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190047967-A1 BLUE LIGHT CUTTING OPTICAL MATERIAL COMPRISING A BENZOTRIAZOLE UV ABSORBER TPMT, PPOX, CYBA CYP3A4 5/4885TSHR 3511/4885MAPT 67/4885
US-10308618-B2 Blue light cutting optical material comprising a benzotriazole UV absorber TPMT, PPOX, CYBA CYP3A4 5/4885TSHR 3511/4885MAPT 67/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.