Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1692133 | 0.88 | KMT2A (0.47) | KAT6AKMT2AMEN1PPARGCYP4F2 | |
| SCHEMBL10268514 | 0.84 | KMT2A (0.50) | KAT6AKMT2AMEN1PPARGCYP4F2 | |
| SCHEMBL1690680 | 0.84 | KMT2A (0.44) | KMT2AMEN1PPARGADORA3ADORA2A | |
| SCHEMBL10272782 | 0.82 | KMT2A (0.50) | KAT6AKMT2AMEN1PPARGCYP4F2 | |
| SCHEMBL24721325 | 0.82 | KMT2A (0.45) | KMT2AMEN1PPARGADORA3ADORA2A | |
| SCHEMBL10268480 | 0.81 | KMT2A (0.55) | KAT6AKMT2AMEN1PPARGCYP4F2 | |
| SCHEMBL1696543 | 0.81 | KMT2A (0.47) | KAT6AKMT2AMEN1PPARGCYP4F2 | |
| SCHEMBL3697259 | 0.79 | CYP4F2 (0.48) | KAT6AKMT2AMEN1PPARGCYP4F2 | |
| SCHEMBL1696458 | 0.78 | KMT2A (0.77) | KMT2AMEN1PPARGL3MBTL1SMN1; SMN2 | |
| SCHEMBL1696343 | 0.78 | L3MBTL1 (0.55) | KAT6AKMT2AMEN1PPARGL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429604-B2 | Six-membered heterocycles useful as serine protease inhibitors | BRISTOL MYERS SQUIBB COMPANY (US) | 2008-09-30 | — | — | US | disclosed |