Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334194 | 0.94 | PPARG (0.45) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL4171314 | 0.89 | PPARG (0.42) | PPARGTHRATHRB | |
| SCHEMBL333835 | 0.87 | KDM4E (0.47) | THRB | |
| SCHEMBL333473 | 0.87 | PPARG (0.60) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL333818 | 0.86 | PPARG (0.52) | PPARGPPARARENAKR1C3AKR1C2 | |
| SCHEMBL333845 | 0.85 | PPARG (0.42) | PPARGPPARATHRATHRB | |
| SCHEMBL333817 | 0.85 | PPARG (0.52) | PPARGPPARARENAKR1C3AKR1C2 | |
| SCHEMBL333222 | 0.84 | PPARG (0.47) | PPARGPPARARENAKR1C3AKR1C2 | |
| SCHEMBL333682 | 0.84 | PTGDR2 (0.46) | PPARGPPARAAKR1C3AKR1C2 | |
| SCHEMBL333680 | 0.83 | PTGES (0.45) | PPARGPPARATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-B1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2011-03-09 | — | — | EP | disclosed |
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |