Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334001 | 0.92 | PTGES (0.47) | PTGESNR1H4MAPK8PPARGPPARA | |
| SCHEMBL333586 | 0.86 | PTGES (0.51) | PTGESNR1H4PPARGPPARACYP2C9 | |
| SCHEMBL3012072 | 0.85 | PTGES (0.51) | PTGESNR1H4MAPK8PPARGPPARA | |
| SCHEMBL334000 | 0.85 | PTGES (0.48) | PTGESNR1H4MAPK8PPARGPPARA | |
| SCHEMBL4021254 | 0.84 | PTGES (0.59) | PTGESNR1H4PPARGPPARACYP2C9 | |
| SCHEMBL334136 | 0.83 | PTGES (0.53) | PTGESNR1H4PPARGPPARACYP2C9 | |
| SCHEMBL4700726 | 0.83 | PTGES (0.53) | PTGESNR1H4MAPK8PPARGPPARA | |
| SCHEMBL4698398 | 0.83 | PTGES (0.55) | PTGESNR1H4PPARGPPARACYP2C9 | |
| SCHEMBL4698605 | 0.82 | PTGES (0.50) | PTGESNR1H4MAPK8PPARGPPARA | |
| SCHEMBL3000522 | 0.82 | PTGES (0.48) | PTGESMAPK8MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-B1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2011-03-09 | — | — | EP | disclosed |