SCHEMBL14074313

SCHEMBL14074313

CC1=C(C#N)C(=O)N(c2ccc(C(=O)O)cc2)C(=O)/C1=C\c1c(C)c(C#N)c(=O)n(-c2ccc(C(=O)O)cc2)c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 8/20 0.38
▸ ALDH1A1 P00352 3/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ MAPT P10636 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ GAA P10253 1/20 0.36
▸ CA12 O43570 3/20 0.36
▸ CA1 P00915 3/20 0.36
▸ CA9 Q16790 3/20 0.36
▸ TSHR P16473 1/20 0.35
▸ CA2 P00918 1/20 0.34
▸ SCN2A Q99250 1/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ POLB P06746 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ APEX1 P27695 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ DDAH1 O94760 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1305383 0.80 HPGD (0.36) ALDH1A1MEN1MAPTKMT2AL3MBTL1
SCHEMBL13850302 0.80 HPGD (0.36) ALDH1A1MEN1MAPTKMT2AL3MBTL1
SCHEMBL1305381 0.80 HPGD (0.36) ALDH1A1MEN1MAPTKMT2AL3MBTL1
SCHEMBL12240030 0.79 HPGD (0.35) ALDH1A1MEN1MAPTKMT2AL3MBTL1
SCHEMBL6682468 0.77 PTPN1 (0.33) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL6678545 0.77 PTPN1 (0.33) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL12239899 0.77 HPGD (0.33) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL12180614 0.72 CA9 (0.49) ALDH1A1MEN1MAPTKMT2AL3MBTL1
SCHEMBL14074486 0.69 ALDH1A1 (0.41) RORCALDH1A1MEN1MAPTKMT2A
SCHEMBL12216628 0.69 HPGD (0.34) ALDH1A1MEN1MAPTKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7422843-B2 Color photographic films comprising support having color developable light sensitive silver halide emulsion layers and color dye-forming couplers, used for high speed print reproduction; storage stability, cinematography, uniformity for quality FUJIFILM CORPORATION (JP) 2008-09-09 — — US disclosed
US-20070248906-A1 Silver halide color photographic light-sensitive material FUJIFILM CORPORATION (JP) 2007-10-25 — — US disclosed
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