Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8251960 | 0.77 | CYP1A2 (0.46) | NAMPTSMN1; SMN2L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL13377645 | 0.77 | BRD4 (0.45) | NAMPTSMN1; SMN2L3MBTL1BRD4CYP1A2 | |
| SCHEMBL10165138 | 0.77 | CYP1A2 (0.44) | NAMPTSMN1; SMN2L3MBTL1BRD4CYP1A2 | |
| SCHEMBL10165136 | 0.76 | CYP1A2 (0.53) | CYP1A2CYP2D6CYP3A4CYP2C19GAA | |
| SCHEMBL8199087 | 0.76 | NAMPT (0.41) | NAMPTSMN1; SMN2L3MBTL1BRD4CYP1A2 | |
| SCHEMBL8203533 | 0.75 | SMN1; SMN2 (0.43) | NAMPTSMN1; SMN2L3MBTL1BRD4CYP1A2 | |
| SCHEMBL8190800 | 0.74 | CYP1A2 (0.51) | NAMPTSMN1; SMN2L3MBTL1BRD4CYP1A2 | |
| SCHEMBL8182098 | 0.74 | NAMPT (0.40) | NAMPTSMN1; SMN2L3MBTL1BRD4CYP1A2 | |
| SCHEMBL7270138 | 0.72 | KMO (0.56) | CYP1A2CYP2D6CYP3A4CYP2C19GAA | |
| SCHEMBL7278244 | 0.72 | CYP3A4 (0.54) | CYP1A2CYP2D6CYP3A4CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109177-A2 | METALLOPROTEASE INHIBITORS CONTAINING A HETEROCYCLIC MOIETY | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008109181-A2 | METALLOPROTEASE INHIBITORS CONTAINING A HETEROCYCLIC MOIETY | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-09-12 | — | — | WO | disclosed |