Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14079267 | 0.84 | GAA (0.51) | NPSR1GAACACNA1G | |
| SCHEMBL8249779 | 0.81 | GAA (0.54) | NPSR1GAACACNA1G | |
| SCHEMBL8245892 | 0.80 | HTR2A (0.51) | LMNA | |
| SCHEMBL917328 | 0.75 | NPSR1 (0.46) | NPSR1LMNACACNA1G | |
| SCHEMBL22053182 | 0.74 | CHRNA7 (0.57) | NOTUMGAA | |
| SCHEMBL31011171 | 0.74 | CHRNA7 (0.57) | NOTUMGAA | |
| SCHEMBL11383229 | 0.73 | NOTUM (0.49) | NOTUMNPSR1LMNA | |
| SCHEMBL8239748 | 0.71 | TAAR1 (0.50) | — | |
| SCHEMBL9377857 | 0.71 | FNTA (0.49) | NPSR1LMNA | |
| SCHEMBL249471 | 0.70 | NOTUM (0.81) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214570-A1 | Therapeutic Agents | ASTRAZENECA AB (SE) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214570-A1 | Therapeutic Agents | NLN, BDNF, GAP43 | NOTUM 1300/4885NPSR1 54/4885GAA 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.