Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12680833 | 0.88 | GSK3B (0.58) | GSK3BEGLN2CLK1HSP90AB1HSP90AA1 | |
| SCHEMBL12680896 | 0.85 | GSK3B (0.39) | GSK3BEGLN2CLK1LMNARAB9A | |
| SCHEMBL12680847 | 0.78 | KDM4E (0.40) | GSK3BEGLN2KDM4EMAPTLIMK1 | |
| SCHEMBL10270036 | 0.77 | GSK3B (0.38) | GSK3BLMNADPP4KDM4ERAB9A | |
| SCHEMBL10270747 | 0.77 | GSK3B (0.53) | GSK3BEGLN2HSP90AB1HSP90AA1LMNA | |
| SCHEMBL12680846 | 0.76 | ALPL (0.37) | GSK3BEGLN2DPP4CNR1 | |
| SCHEMBL3603974 | 0.75 | EGLN2 (0.35) | GSK3BEGLN2HSP90AB1HSP90AA1LMNA | |
| SCHEMBL12680862 | 0.75 | GSK3B (0.36) | GSK3BEGLN2 | |
| SCHEMBL3608624 | 0.75 | GSK3B (0.53) | GSK3BEGLN2LIMK1 | |
| SCHEMBL10270549 | 0.73 | GSK3B (0.47) | GSK3BEGLN2CLK1HSP90AB1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113469-A2 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-09-25 | — | — | WO | disclosed |