SCHEMBL1407977

SCHEMBL1407977

O=C(O)c1ccc2c(c1)COC2=O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
LMNA P02545 2/20 0.56
GAA P10253 1/20 0.56
ALDH1A1 P00352 2/20 0.54
SRD5A2 P31213 4/20 0.53
SRD5A1 P18405 3/20 0.53
PRF1 P14222 5/20 0.52
NPC1 O15118 1/20 0.51
MAOA P21397 2/20 0.50
MAOB P27338 2/20 0.50
RECQL P46063 1/20 0.50
TTR P02766 1/20 0.49
KDM4E B2RXH2 1/20 0.48
PTPRC P08575 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30625936 1.00 MAPT (0.56) MAPTLMNAGAAALDH1A1SRD5A2
Ammonia Solution, Strong SCHEMBL7075828 0.98 MAPT (0.54) MAPTLMNAGAAALDH1A1SRD5A2
Hydrochloric Acid SCHEMBL7009662 0.98 MAPT (0.54) MAPTLMNAGAAALDH1A1SRD5A2
Terephthalic Acid SCHEMBL7611766 0.98 MAPT (0.54) MAPTLMNAGAAALDH1A1SRD5A2
SCHEMBL7071686 0.88 MAPT (0.49) MAPTLMNAGAAALDH1A1SRD5A2
SCHEMBL6427216 0.86 KMT2A (0.51) ALDH1A1SRD5A2SRD5A1MAOAMAOB
Oxazolidine SCHEMBL27667425 0.85 PRF1 (0.44) MAPTLMNAGAAALDH1A1SRD5A2
SCHEMBL31490188 0.84 PRF1 (0.66) MAPTLMNAGAAALDH1A1PRF1
SCHEMBL3655528 0.84 PRF1 (0.66) MAPTLMNAGAAALDH1A1PRF1
SCHEMBL3038326 0.84 MAPT (0.54) MAPTLMNAGAAALDH1A1PRF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4570901-A1 METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS Buddhist Tzu Chi Medical Foundation (TW) 2025-06-18 EP claimed
CN-120137900-A Method for selectively removing undifferentiated pluripotent stem cells 佛教慈济医疗财团法人 2025-06-13 CN claimed
US-20250188411-A1 METHOD FOR SELECTIVE REMOVAL OF UNDIFFERENTIATED PLURIPOTENT STEM CELLS BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) 2025-06-12 US claimed
CN-119775242-A Method for synthesizing 5-cyanophthalide 内蒙古源宏精细化工有限公司 2025-04-08 CN claimed
CN-118420576-A Amino acid-like guided phthalide analogues and uses thereof 河南农业大学 2024-08-02 CN claimed
CN-115477577-B New method for preparing 2-methyl-4-acetyl benzoic acid and derivatives thereof 台州臻挚生物科技有限公司 2024-03-15 CN claimed
CN-116444298-B Metal texture rock plate 广东兴辉陶瓷集团有限公司 2024-01-05 CN claimed
CN-117285491-A Amino acid-like guided phthalide analogues and uses thereof 河南农业大学 2023-12-26 CN claimed
CN-116444298-A Metal texture rock plate 广东兴辉陶瓷集团有限公司 2023-07-18 CN claimed
CN-115477577-A Novel method for preparing 2-methyl-4-acetylbenzoic acid and derivatives thereof 台州臻挚生物科技有限公司 2022-12-16 CN claimed
EP-1140886-A1 METHOD FOR THE PREPARATION OF 5-CYANOPHTHALIDE H. LUNDBECK A/S (DK) 2001-10-10 EP claimed
EP-1123284-A1 METHOD FOR THE PREPARATION OF CITALOPRAM H. Lundbeck A/S (DK) 2001-08-16 EP claimed
WO-2001053284-A1 PROCESS FOR THE PREPARATION OF 5-CARBOXYPHTHALIDE AND ITS USE FOR THE PRODUCTION OF CITALOPRAM INFOSINT SA (CH) 2001-07-26 WO claimed
EP-1118614-A2 Process for the preparation of 5-carboxyphthalide Norpharma SpA (IT) 2001-07-25 EP claimed
WO-2001051477-A1 METHOD FOR THE PREPARATION OF 5-CYANOPHTHALIDE H. LUNDBECK A/S (DK) 2001-07-19 WO claimed
WO-2001032643-A1 METHOD FOR THE PREPARATION OF 5-CARBOXYPHTHALIDE H. LUNDBECK A/S (DK) 2001-05-10 WO claimed
WO-2001032642-A1 METHOD FOR THE PREPARATION OF 5-CARBOXYPHTHALIDE H. LUNDBECK A/S (DK) 2001-05-10 WO claimed
WO-2000044738-A1 METHOD FOR THE PREPARATION OF 5-CYANOPHTHALIDE H. LUNDBECK A/S (DK) 2000-08-03 WO claimed
WO-2000039112-A1 METHOD FOR THE PREPARATION OF 5-CYANOPHTHALIDE H. LUNDBECK A/S (DK) 2000-07-06 WO claimed
WO-2000023431-A1 METHOD FOR THE PREPARATION OF CITALOPRAM H. LUNDBECK A/S (DK) 2000-04-27 WO claimed