Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7075828

N.O=C(O)c1ccc2c(c1)COC2=O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
LMNA P02545 2/20 0.54
GAA P10253 1/20 0.54
ALDH1A1 P00352 2/20 0.52
SRD5A2 P31213 4/20 0.51
SRD5A1 P18405 3/20 0.51
PRF1 P14222 5/20 0.51
NPC1 O15118 1/20 0.50
RECQL P46063 1/20 0.49
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.48
TTR P02766 1/20 0.47
KDM4E B2RXH2 1/20 0.47
PTPRC P08575 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30625936 0.98 MAPT (0.56) MAPTLMNAGAAALDH1A1SRD5A2
SCHEMBL1407977 0.98 MAPT (0.56) MAPTLMNAGAAALDH1A1SRD5A2
Hydrochloric Acid SCHEMBL7009662 0.97 MAPT (0.54) MAPTLMNAGAAALDH1A1SRD5A2
Terephthalic Acid SCHEMBL7611766 0.97 MAPT (0.54) MAPTLMNAGAAALDH1A1SRD5A2
SCHEMBL7071686 0.87 MAPT (0.49) MAPTLMNAGAAALDH1A1SRD5A2
SCHEMBL6427216 0.84 KMT2A (0.51) ALDH1A1SRD5A2SRD5A1MAOAMAOB
Oxazolidine SCHEMBL27667425 0.83 PRF1 (0.44) MAPTLMNAGAAALDH1A1SRD5A2
SCHEMBL3655528 0.83 PRF1 (0.66) MAPTLMNAGAAALDH1A1PRF1
SCHEMBL31490188 0.83 PRF1 (0.66) MAPTLMNAGAAALDH1A1PRF1
SCHEMBL3038326 0.83 MAPT (0.54) MAPTLMNAGAAALDH1A1PRF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1321464-A1 Process for the preparation of 5-cyanophthalide and intermediates useful therein ICROM S.p.A. (IT) 2003-06-25 EP disclosed