Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11944495 | 0.92 | MAPT (0.47) | MAPTALDH1A1DCTPP1POLBCYP3A4 | |
| SCHEMBL11944379 | 0.85 | MAPT (0.47) | MAPTALDH1A1DCTPP1POLBCYP3A4 | |
| SCHEMBL11944914 | 0.84 | POLB (0.47) | MAPTALDH1A1DCTPP1POLBCYP3A4 | |
| SCHEMBL11944862 | 0.81 | ALDH1A1 (0.55) | MAPTALDH1A1DCTPP1POLBCYP3A4 | |
| SCHEMBL11944484 | 0.80 | MAPT (0.41) | MAPTALDH1A1DCTPP1POLBCYP3A4 | |
| SCHEMBL11944879 | 0.78 | POLB (0.47) | MAPTALDH1A1DCTPP1POLBCYP3A4 | |
| SCHEMBL11944884 | 0.78 | MAPT (0.48) | MAPTALDH1A1DCTPP1POLBCYP3A4 | |
| SCHEMBL11945288 | 0.77 | POLB (0.45) | MAPTALDH1A1DCTPP1POLBCYP3A4 | |
| SCHEMBL11944880 | 0.77 | POLB (0.46) | MAPTALDH1A1DCTPP1POLBCYP3A4 | |
| SCHEMBL11944345 | 0.77 | ALDH1A1 (0.49) | MAPTALDH1A1DCTPP1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115381-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2008-09-25 | — | — | WO | disclosed |