Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.59 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4228524 | 0.92 | CYP19A1 (0.74) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5751218 | 0.85 | CYP19A1 (0.73) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3177161 | 0.84 | MKNK1 (0.56) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4861343 | 0.83 | CYP19A1 (0.71) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14129887 | 0.83 | CYP2D6 (1.00) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12129582 | 0.82 | CYP19A1 (0.69) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28046302 | 0.82 | CYP3A4 (0.74) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13527207 | 0.81 | CYP2D6 (0.94) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31483083 | 0.80 | CHRNB2 (0.62) | MKNK2TAAR1LTA4HPLA2G2A | |
| SCHEMBL1622662 | 0.80 | CHRNB2 (0.62) | MKNK2TAAR1LTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008106204-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X-PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |