SCHEMBL1408387

SCHEMBL1408387

C=C(CCCC)C(=O)O.CO[SiH](OC)OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.39
CES2 O00748 1/20 0.39
THRB P10828 1/20 0.37
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37
PGGT1B P53609 1/20 0.37
ALDH1A1 P00352 3/20 0.37
AKR1B1 P15121 1/20 0.37
TP53 P04637 1/20 0.37
GPR84 Q9NQS5 7/20 0.35
PPARG P37231 7/20 0.35
PPARD Q03181 7/20 0.35
PPARA Q07869 7/20 0.35
HDAC11 Q96DB2 5/20 0.35
TSHR P16473 4/20 0.35
PTPN1 P18031 3/20 0.35
TLR2 O60603 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
FABP4 P15090 2/20 0.35
SLC22A6 Q4U2R8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22623 0.87
SCHEMBL6916130 0.87 CES1 (0.50) CES1CES2THRBFNTAFNTB
SCHEMBL8433150 0.85 CES1 (0.44) CES1CES2THRBFNTAFNTB
Bromide SCHEMBL30933210 0.85 CES1 (0.48) CES1CES2THRBFNTAFNTB
Hydrochloric Acid SCHEMBL9902114 0.85 CES1 (0.48) CES1CES2THRBFNTAFNTB
SCHEMBL29143542 0.85 CES1 (0.48) CES1CES2THRBFNTAFNTB
Ethylene SCHEMBL7561864 0.85 CES1 (0.48) CES1CES2THRBFNTAFNTB
SCHEMBL2578200 0.85 CES1 (0.48) CES1CES2THRBFNTAFNTB
SCHEMBL5053405 0.85 CES1 (0.48) CES1CES2THRBFNTAFNTB
SCHEMBL11501485 0.85 CES1 (0.48) CES1CES2THRBFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1637561-B1 Gloss reducing polymer composition ROHM & HAAS (US) 2014-02-26 EP disclosed
CN-102775640-A Functionalized nanoparticles CIBA SC HOLDING AG 2012-11-14 CN disclosed
US-7989082-B2 Composite with gloss reducing polymer composition ROHM AND HAAS COMPANY (US) 2011-08-02 US disclosed
EP-2295495-A1 Gloss reducing polymer composition Rohm and Haas Company (US) 2011-03-16 EP disclosed
US-20100317819-A1 SURFACE-MODIFIED NANOPARTICLES COMPRISING A CATIONIC COLORANT FOR USE IN COLOR FILTERS CIBA CORPORATION (US) 2010-12-16 US disclosed
EP-2144967-A2 SURFACE-MODIFIED NANOPARTICLES COMPRISING A CATIONIC COLORANT FOR USE IN COLOR FILTERS BASF SE (DE) 2010-01-20 EP disclosed
US-20090191400-A1 Composite with gloss reducing polymer composition ROHM AND HAAS COMPANY 2009-07-30 US disclosed
US-7557158-B2 Gloss reducing polymer composition ROHM AND HAAS COMPANY (US) 2009-07-07 US disclosed
US-20090099282-A1 Functionalized nanoparticles CIBA SPECIALTY CHEMICALS CORP. 2009-04-16 US disclosed
WO-2008107304-A2 SURFACE-MODIFIED NANOPARTICLES COMPRISING A CATIONIC COLORANT FOR USE IN COLOR FILTERS BASF SE (CH) 2008-09-12 WO disclosed
EP-1883676-A1 FUNCTIONALIZED NANOPARTICLES Ciba Specialty Chemicals Holding Inc. (CH) 2008-02-06 EP disclosed
WO-2006125736-A1 FUNCTIONALIZED NANOPARTICLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-11-30 WO disclosed
EP-1637561-A2 Gloss reducing polymer composition Rohm and Haas Company (US) 2006-03-22 EP disclosed
US-20060058460-A1 Gloss reducing polymer composition ROHM AND HAAS COMPANY 2006-03-16 US disclosed
US-20040213992-A1 Electrically insulating material in tape form, insulated article and aqueous dispersion type acrylic pressure sensitive adhesive agent for insulating material NITTO DENKO CORPORATION (JP) 2004-10-28 US disclosed
EP-1114734-A1 RESIN COMPOSITION FOR INK-JET RECORDING SHEET AND RECORDING SHEET MADE WITH THE SAME DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2001-07-11 EP disclosed
EP-0461246-B1 METHOD FOR GRAFTING FUNCTIONS ONTO CHLORINATED (CO)POLYMERS, AND COMPOSITIONS AND SHAPED OBJECTS CENTRE NAT RECH SCIENT (FR) 1995-08-09 EP disclosed
US-5266637-A Process for grafting functions onto chlorinated (co)polymers, compositions and shaped objects CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1993-11-30 US disclosed
EP-0461246-A1 METHOD FOR GRAFTING FUNCTIONS ONTO CHLORINATED (CO)POLYMERS, AND COMPOSITIONS AND SHAPED OBJECTS. CENTRE NAT RECH SCIENT (FR) 1991-12-18 EP disclosed
WO-1991009884-A1 METHOD FOR GRAFTING FUNCTIONS ONTO CHLORINATED (CO)POLYMERS, AND COMPOSITIONS AND SHAPED OBJECTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1991-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317819-A1 SURFACE-MODIFIED NANOPARTICLES COMPRISING A CATIONIC COLORANT FOR USE IN COLOR FILTERS CD63, CD59, ITGAM CES1 3783/4885CES2 2326/4885THRB 4124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.