Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11659644 | 0.77 | ALDH1A1 (0.44) | ALDH1A1ALOX15HSD17B10LMNAPTPN1 | |
| SCHEMBL11659646 | 0.77 | ALDH1A1 (0.44) | ALDH1A1ALOX15HSD17B10LMNAPTPN1 | |
| SCHEMBL14083220 | 0.76 | ALDH1A1 (0.33) | ALDH1A1ALOX15HSD17B10LMNAPTPN1 | |
| SCHEMBL11039206 | 0.76 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10LMNAPTPN1 | |
| SCHEMBL11039208 | 0.76 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10LMNAPTPN1 | |
| SCHEMBL14023892 | 0.75 | ALDH1A1 (0.33) | ALDH1A1ALOX15HSD17B10LMNACYP3A4 | |
| SCHEMBL271027 | 0.71 | ALDH1A1 (0.50) | ALDH1A1ALOX15HSD17B10LMNAPTPN1 | |
| SCHEMBL221749 | 0.71 | ALDH1A1 (0.50) | ALDH1A1ALOX15HSD17B10LMNAPTPN1 | |
| SCHEMBL74779 | 0.71 | ALDH1A1 (0.50) | ALDH1A1ALOX15HSD17B10LMNAPTPN1 | |
| SCHEMBL7862517 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008106225-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |