SCHEMBL1408401

SCHEMBL1408401

NCC(N)CC(O)CCO

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1408854 0.86 USP2 (0.31)
SCHEMBL1408428 0.84 USP2 (0.33)
SCHEMBL15204260 0.82 THRB (0.52) THRBALDH1A1
SCHEMBL1047202 0.79
SCHEMBL183935 0.78 THRB (0.42) THRB
SCHEMBL5432682 0.78 GRIK1 (0.33) ALDH1A1
SCHEMBL9419614 0.77 THRB (0.39) THRBALDH1A1
SCHEMBL910640 0.76 THRB (0.40) THRBALDH1A1
SCHEMBL18541532 0.76
SCHEMBL2350696 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2295438-B2 PROCESS FOR PRODUCING HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND, AND CATALYST COMPOSITION FOR THE PRODUCTION OF POLYURETHANE RESIN USING THE HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND TOSOH CORP (JP) 2025-03-26 EP disclosed
EP-2295438-B1 PROCESS FOR PRODUCING HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND, AND CATALYST COMPOSITION FOR THE PRODUCTION OF POLYURETHANE RESIN USING THE HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND TOSOH CORP (JP) 2015-03-18 EP disclosed
US-20110077376-A1 PROCESS FOR PRODUCING HYDROXYALKYLTRIETHYLENEDIAMINE, AND CATALYST COMPOSITION FOR THE PRODUCTION OF POLYURETHANE RESIN USING IT TOSOH CORPORATION (JP) 2011-03-31 US disclosed
EP-2295438-A1 PROCESS FOR PRODUCING HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND, AND CATALYST COMPOSITION FOR THE PRODUCTION OF POLYURETHANE RESIN USING THE HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND Tosoh Corporation (JP) 2011-03-16 EP disclosed
US-4097478-A GAS PHASE, FROM DIOL AND DIAMINE, ZINC CATALYST TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) 1978-06-27 US disclosed