SCHEMBL14084618

SCHEMBL14084618

Cc1cccc2ccc(N=Nc3c(SOOO)cc4cc(S(=O)(=O)O)cc(Nc5nc(Cl)nc(SO)n5)c4c3O)cc12

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FUT8 Q9BYC5 1/20 0.44
▸ MAPK1 P28482 2/20 0.33
▸ GAA P10253 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ ENPP2 Q13822 3/20 0.33
▸ CYP1A2 P05177 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ DNASE1L3 Q13609 1/20 0.32
▸ CARM1 Q86X55 1/20 0.31
▸ PRMT1 Q99873 1/20 0.31
▸ PHLPP2 Q6ZVD8 1/20 0.31
▸ PTPN11 Q06124 1/20 0.31
▸ GLO1 Q04760 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14020348 0.95 FUT8 (0.43) FUT8MAPK1GAAMAPTKMT2A
SCHEMBL14084619 0.87 FUT8 (0.46) FUT8MAPK1GAAMAPTKMT2A
SCHEMBL14020931 0.80 FUT8 (0.52) FUT8MAPK1GAAMAPTKMT2A
SCHEMBL14071634 0.80 FUT8 (0.52) FUT8MAPK1GAAMAPTKMT2A
SCHEMBL12589891 0.79 FUT8 (0.65) FUT8MAPK1KMT2AENPP2CYP1A2
SCHEMBL14444809 0.77 FUT8 (0.51) FUT8MAPK1KMT2ATDP1ENPP2
SCHEMBL14012420 0.77 FUT8 (0.43) FUT8ENPP2CARM1PRMT1
SCHEMBL14084616 0.77 FUT8 (0.42) FUT8
SCHEMBL13815348 0.76 FUT8 (0.53) FUT8MAPK1KMT2ATDP1ENPP2
SCHEMBL14084627 0.76 FUT8 (0.42) FUT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-08-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group TST, IK, NOX5 FUT8 672/4885MAPK1 1357/4885GAA 3168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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