SCHEMBL1408477

SCHEMBL1408477

CC(C)C1(c2ccc(O)cc2)CCCC(C)(c2ccc(O)cc2)C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
SLC6A4 P31645 10/20 0.35
SLC6A3 Q01959 10/20 0.35
CYP3A4 P08684 2/20 0.34
ALOX15 P16050 2/20 0.34
TSHR P16473 2/20 0.34
TP53 P04637 1/20 0.34
SLC6A2 P23975 3/20 0.33
CHRM2 P08172 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
HTR2A P28223 1/20 0.33
OPRK1 P41145 1/20 0.33
HTR2B P41595 1/20 0.33
KCNH2 Q12809 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9322798 0.82 ESR2 (0.50) ESR1ESR2CYP3A4ALOX15ALDH1A1
SCHEMBL3682201 0.80 ESR2 (0.39) ESR1ESR2SLC6A4SLC6A3SLC6A2
SCHEMBL1495106 0.78 ESR2 (0.54) ESR1ESR2CYP3A4ALOX15ALDH1A1
SCHEMBL6537269 0.77 ESR1 (0.36) ESR1ESR2SLC6A4SLC6A3CYP3A4
SCHEMBL5241008 0.74 ESR2 (0.60) ESR1ESR2SLC6A4SLC6A3CYP3A4
SCHEMBL1516123 0.73 ESR2 (0.61) ESR1ESR2SLC6A4SLC6A3CYP3A4
SCHEMBL4492789 0.70 ESR2 (0.52) ESR1ESR2SLC6A4SLC6A3CYP3A4
SCHEMBL9972164 0.68 ESR2 (0.38) ESR1ESR2SLC6A4SLC6A3KCNH2
SCHEMBL2270713 0.68 CYP3A4 (0.70) ESR1ESR2SLC6A4SLC6A3CYP3A4
SCHEMBL13755345 0.66 SLC6A4 (0.65) SLC6A4SLC6A3CYP3A4ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1581594-B1 POLYCARBONATE MOLDING COMPOSITIONS AND ARTICLES WITH IMPROVED SURFACE AESTHETICS SABIC INNOVATIVE PLASTICS IP (NL) 2013-03-27 EP claimed
JP-2007514854-A 2007-06-07 JP claimed
EP-1697465-A2 POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION GENERAL ELECTRIC COMPANY (US) 2006-09-06 EP claimed
EP-1581594-A1 POLYCARBONATE MOLDING COMPOSITIONS AND ARTICLES WITH IMPROVED SURFACE AESTHETICS GENERAL ELECTRIC COMPANY (US) 2005-10-05 EP claimed
WO-2005061623-A2 POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION GENERAL ELECTRIC COMPANY (US) 2005-07-07 WO claimed
US-20050137310-A1 Polymer nanocomposites and methods for their preparation CITIBANK, N.A., AS COLLATERAL AGENT 2005-06-23 US claimed
US-6825266-B2 POLYCARBONATESILOXANE BLOCK COPOLYMER AND POLYOXYALKYLENE GLYCOL FLOW CONTROL AGENT; LOW TEMPERATURE IMPACT STRENGTH, COLD RESISTANCE, DUCTILITY, MELT PROCESSABILITY, AND FIREPROOF GENERAL ELECTRIC COMPANY 2004-11-30 US claimed
WO-2004061004-A1 POLYCARBONATE MOLDING COMPOSITIONS AND ARTICLES WITH IMPROVED SURFACE AESTHETICS GENERAL ELECTRIC COMPANY (US) 2004-07-22 WO claimed
US-20040127635-A1 POLYCARBONATE MOLDING COMPOSITIONS AND ARTICLES WITH IMPROVED SURFACE AESTHETICS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2004-07-01 US claimed
CN-120019101-A Polycarbonate copolymer and molded article comprising the same 帝人株式会社 2025-05-16 CN disclosed
WO-2024150594-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING SAME 帝人株式会社 2024-07-18 WO disclosed
WO-2024075642-A1 POLYCARBONATE COPOLYMER AND MOLDED ARTICLE COMPRISING SAME 帝人株式会社 2024-04-11 WO disclosed
CN-116348529-A Polycarbonate resin composition and circuit molded article for communication device 帝人株式会社 2023-06-27 CN disclosed
CN-113166390-B Thermoplastic resin for lens and lens comprising same 帝人株式会社 2023-04-04 CN disclosed
WO-2005061623-A2 POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION GENERAL ELECTRIC COMPANY (US) 2005-07-07 WO disclosed
US-20050137428-A1 METHODS FOR PREPARING CYCLOALKYLIDENE BISPHENOLS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2005-06-23 US disclosed
US-20050137310-A1 Polymer nanocomposites and methods for their preparation CITIBANK, N.A., AS COLLATERAL AGENT 2005-06-23 US disclosed
US-6825266-B2 POLYCARBONATESILOXANE BLOCK COPOLYMER AND POLYOXYALKYLENE GLYCOL FLOW CONTROL AGENT; LOW TEMPERATURE IMPACT STRENGTH, COLD RESISTANCE, DUCTILITY, MELT PROCESSABILITY, AND FIREPROOF GENERAL ELECTRIC COMPANY 2004-11-30 US disclosed
WO-2004061004-A1 POLYCARBONATE MOLDING COMPOSITIONS AND ARTICLES WITH IMPROVED SURFACE AESTHETICS GENERAL ELECTRIC COMPANY (US) 2004-07-22 WO disclosed
US-20040127635-A1 POLYCARBONATE MOLDING COMPOSITIONS AND ARTICLES WITH IMPROVED SURFACE AESTHETICS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2004-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050137428-A1 METHODS FOR PREPARING CYCLOALKYLIDENE BISPHENOLS NR3C2, RCOR1, CBR1 ESR1 62/4885ESR2 109/4885SLC6A4 2239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.