Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.50 |
| ▸ | ESR1 | P03372 | 5/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1495106 | 0.91 | ESR2 (0.54) | ESR2ESR1MMP2MMP9MAPT | |
| SCHEMBL5241008 | 0.86 | ESR2 (0.60) | ESR2ESR1MMP2MMP9MAPT | |
| SCHEMBL1516123 | 0.84 | ESR2 (0.61) | ESR2ESR1MMP2MMP9MAPT | |
| SCHEMBL1408477 | 0.82 | ESR1 (0.39) | ESR2ESR1MMP2MMP9MAPT | |
| SCHEMBL4492789 | 0.81 | ESR2 (0.52) | ESR2ESR1MMP2MMP9MAPT | |
| SCHEMBL21755391 | 0.76 | ESR2 (0.40) | ESR2ESR1MMP2MMP9OPRD1 | |
| Phenol SCHEMBL4491407 | 0.74 | CA12 (0.48) | ESR2ESR1MMP2MMP9MAPT | |
| SCHEMBL669016 | 0.74 | ESR2 (0.61) | ESR2ESR1MMP2MMP9MAPT | |
| SCHEMBL1516011 | 0.74 | ESR2 (0.41) | ESR2ESR1MMP2MMP9ALDH1A1 | |
| SCHEMBL7184823 | 0.74 | ESR2 (0.46) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344999-A | Monomers with high glass transition temperatures and with ductility | GENERAL ELECTRIC COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| US-5344999-A | Monomers with high glass transition temperatures and with ductility | GENERAL ELECTRIC COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0602874-A1 | 1,3-Bis(4-hydroxyphenyl)-1,3-dialkylcyclohexanes and polycarbonates prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 1994-06-22 | — | — | EP | disclosed |
| EP-0602874-A1 | 1,3-Bis(4-hydroxyphenyl)-1,3-dialkylcyclohexanes and polycarbonates prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 1994-06-22 | — | — | EP | disclosed |
| US-5281688-A | Polycarbonate from 1,3-bis(4-hydroxyphenyl)-1,3-dialkylcyclohexanes | GENERAL ELECTRIC COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-5281688-A | Polycarbonate from 1,3-bis(4-hydroxyphenyl)-1,3-dialkylcyclohexanes | GENERAL ELECTRIC COMPANY (US) | 1994-01-25 | — | — | US | disclosed |