Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.53 |
| ▸ | PTPRC | P08575 | 4/20 | 0.53 |
| ▸ | CDC25B | P30305 | 3/20 | 0.53 |
| ▸ | PTPRF | P10586 | 1/20 | 0.53 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28277167 | 0.94 | BACE1 (0.57) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL29809142 | 0.94 | BACE1 (0.57) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL3444897 | 0.86 | CDC25B (0.57) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL8240772 | 0.86 | BACE1 (0.48) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL3713042 | 0.83 | MAPK1 (0.61) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL13475649 | 0.83 | BACE1 (0.46) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL31682254 | 0.83 | MAPK1 (0.61) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL7119051 | 0.82 | CDC25B (0.53) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL9120460 | 0.81 | PTPN1 (0.50) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL978806 | 0.80 | BACE1 (0.48) | BACE1PTPN1PTPRCCDC25BPTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143602-B | Indenone and indazolone derivatives with antioxidant activity, and synthetic method and application thereof | 西南大学 | 2024-10-22 | — | — | CN | disclosed |
| CN-116554104-A | Indenone and indazolone derivatives with antioxidant activity, and synthetic method and application thereof | 西南大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-116143602-A | Indenone and indazolone derivatives with antioxidant activity, and synthetic method and application thereof | 西南大学 | 2023-05-23 | — | — | CN | disclosed |
| US-20200392259-A1 | ORTHOMETALLATED CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION AND COPOLYMERIZATION | ARZOUMANIDIS GREGORY G (US) | 2020-12-17 | — | — | US | disclosed |
| US-20200207982-A1 | POLYAMIDE BLENDS | DOW SILICONES CORP (US) | 2020-07-02 | — | — | US | disclosed |
| EP-3655482-A1 | POLYAMIDE BLENDS | Dow Silicones Corporation (US) | 2020-05-27 | — | — | EP | disclosed |
| WO-2019018094-A1 | POLYAMIDE BLENDS | DOW SILICONES CORPORATION (US) | 2019-01-24 | — | — | WO | disclosed |
| EP-2294101-B1 | POLYMERS MODIFIED BY SILANES | DOW SILICONES CORP (US) | 2018-10-17 | — | — | EP | disclosed |
| EP-2521752-B1 | ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP | DOW CORNING (US) | 2017-10-25 | — | — | EP | disclosed |
| US-9493615-B2 | Organopolysiloxanes containing an unsaturated group | DOW CORNING CORPORATION (US) | 2016-11-15 | — | — | US | disclosed |
| WO-2010000478-A1 | MODIFIED POLYOLEFINS | DOW CORNING CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |
| US-6790998-B2 | SUCH AS 5-METHYL-3-PHENYL)-INDEN-1-ONE FOR ENANTIOSELECTIVE PREPARATION OF TOLTERODINE AND ANALOGUES/SALTS THEREOF | PHARMACIA AB (SE) | 2004-09-14 | — | — | US | disclosed |
| EP-0776913-B1 | High molecular weight copolymers | BASELL POLYOLEFINE GMBH (DE) | 2004-02-04 | — | — | EP | disclosed |
| US-20030191348-A1 | Such as 5-methyl-3-phenyl)-inden-1-one for enantioselective preparation of tolterodine and analogues/salts thereof | ANDERSSON PHER G (SE) | 2003-10-09 | — | — | US | disclosed |
| EP-1270614-A2 | Copolymers containing propylene and alpha-olefin comonomer | Basell Polyolefine GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| EP-0790076-B1 | Catalysts containing metallocenes with arylsubstituted indenyl derivatives as ligands, process and intermediates for the preparation of these metallocenes and their use | BASELL POLYOLEFINE GMBH (DE) | 2001-12-05 | — | — | EP | disclosed |
| EP-0576970-B1 | Metallocenes with arylsubstituted indenyl-derivatives as ligands, process for their preparation and their use as catalysts | HOECHST AG (DE) | 1998-01-14 | — | — | EP | disclosed |
| EP-0790076-A2 | Catalysts containing metallocenes with arylsubstituted indenyl derivatives as ligands, process and intermediates for the preparation of these metallocenes and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0776913-A2 | High molecular weight copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-04 | — | — | EP | disclosed |
| EP-0576970-A1 | Metallocenes with arylsubstituted indenyl-derivatives as ligands, process for their preparation and their use as catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191348-A1 | Such as 5-methyl-3-phenyl)-inden-1-one for enantioselective preparation of tolterodine and analogues/salts thereof | CYP1B1, CYP4B1, THRB | BACE1 2921/4885PTPN1 3330/4885PTPRC 3627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.