SCHEMBL1408548

SCHEMBL1408548

OCCc1ccsc1-c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.54
ALOX15 P16050 1/20 0.54
MAPK1 P28482 1/20 0.54
KMT2A Q03164 1/20 0.54
TDP1 Q9NUW8 1/20 0.40
PTGS2 P35354 1/20 0.39
BCAT2 O15382 1/20 0.37
ALDH1A1 P00352 3/20 0.36
PDPK1 O15530 1/20 0.34
PTGS1 P23219 1/20 0.34
KDM4E B2RXH2 1/20 0.33
LTB4R Q15722 4/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
RECQL P46063 1/20 0.32
TKT P29401 1/20 0.32
FFAR1 O14842 1/20 0.32
BACE1 P56817 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5111011 0.84 TP53 (0.57) TP53ALOX15MAPK1KMT2APTGS2
SCHEMBL5174119 0.83 TP53 (0.34) TP53ALOX15MAPK1KMT2ATDP1
SCHEMBL901920 0.81 KMT2A (0.50) TP53ALOX15MAPK1KMT2APTGS2
SCHEMBL27574509 0.78 TP53 (0.47) TP53ALOX15MAPK1KMT2APTGS2
SCHEMBL5171835 0.77 DPP4 (0.41) TP53ALOX15MAPK1KMT2ATDP1
SCHEMBL7386191 0.76 KMT2A (0.53) TP53ALOX15MAPK1KMT2APTGS2
SCHEMBL27659211 0.76 TP53 (0.53) TP53ALOX15MAPK1KMT2APTGS2
SCHEMBL1520751 0.76 KMT2A (0.71) TP53ALOX15MAPK1KMT2ATDP1
SCHEMBL27824748 0.75 TP53 (0.45) TP53ALOX15MAPK1KMT2A
SCHEMBL28329506 0.75 TP53 (0.45) TP53ALOX15MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1560060-B1 Polarizing or photochromic plastic lens, coated sheet-like light element and method of its production MGC FILSEET CO LTD (JP) 2011-03-09 EP disclosed
US-7350917-B2 Light control plastic lens, coated sheet-like light control element for the lens production, and a production method for light control plastic lens MGC FILSEET CO., LTD. (JP) 2008-04-01 US disclosed
US-20050168690-A1 Light control plastic lens, coated sheet-like light control element for the lens production, and a production method for light control plastic lens FUJI KASEI CO., LTD. (JP) 2005-08-04 US disclosed
EP-1560060-A1 Polarizing or photochromic plastic lens, coated sheet-like light element and method of its production Fuji Kasei Co., Ltd. (JP) 2005-08-03 EP disclosed