Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13870045 | 0.91 | FDPS (0.51) | FDPSLTA4HCYP1A2TSHRHDAC1 | |
| SCHEMBL6950642 | 0.83 | ADORA2A (0.53) | FDPSLTA4HCYP1A2TSHRHDAC1 | |
| SCHEMBL3691691 | 0.81 | FDPS (0.48) | FDPSLTA4HCYP1A2TSHRHDAC1 | |
| SCHEMBL5017550 | 0.81 | FDPS (0.50) | FDPSLTA4HCYP1A2TSHRHDAC1 | |
| SCHEMBL8649807 | 0.80 | FDPS (0.47) | FDPSLTA4HCYP1A2TSHRHDAC1 | |
| SCHEMBL5017010 | 0.80 | FDPS (0.49) | FDPSLTA4HCYP1A2TSHRHDAC1 | |
| SCHEMBL11249434 | 0.80 | FDPS (0.49) | FDPSLTA4HCYP1A2TSHRHDAC1 | |
| SCHEMBL5017009 | 0.80 | FDPS (0.49) | FDPSLTA4HCYP1A2TSHRHDAC1 | |
| SCHEMBL7102528 | 0.80 | FDPS (0.49) | FDPSLTA4HCYP1A2TSHRHDAC1 | |
| SCHEMBL31024294 | 0.79 | FDPS (0.51) | FDPSLTA4HCYP1A2TSHRHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313751-B1 | NEW MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2008-09-17 | — | — | EP | disclosed |