Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27672858 | 0.90 | KMT2A (0.34) | KMT2ACYP1A2CYP2D6TMEM97SIGMAR1 | |
| SCHEMBL15920365 | 0.90 | KMT2A (0.34) | KMT2ACYP1A2CYP2D6TMEM97SIGMAR1 | |
| SCHEMBL6128387 | 0.87 | KMT2A (0.41) | KMT2ACYP1A2CYP2D6TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28294310 | 0.86 | KMT2A (0.40) | KMT2ACYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL9812776 | 0.85 | RELA (0.45) | KMT2ACYP1A2CYP2D6MAPTAPP | |
| SCHEMBL13138317 | 0.85 | RELA (0.45) | KMT2ACYP1A2CYP2D6MAPTAPP | |
| SCHEMBL6128338 | 0.84 | MAPT (0.42) | KMT2ACYP1A2CYP2D6MAPTAPP | |
| Hydrochloric Acid SCHEMBL11791882 | 0.84 | RELA (0.44) | KMT2ACYP1A2CYP2D6MAPTAPP | |
| SCHEMBL10267718 | 0.81 | MAPT (0.36) | KMT2ACYP1A2CYP2D6MAPTAPP | |
| SCHEMBL10268981 | 0.80 | RELA (0.42) | KMT2AMAPTAPPMAOBRELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080184495-A1 | Dye composition comprising a reactive silicone and a fluorescent dye, and dyeing process using the composition | L'OREAL S.A. (FR) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080184495-A1 | Dye composition comprising a reactive silicone and a fluorescent dye, and dyeing process using the composition | KRT18, VIM, CD44 | KMT2A 1319/4885CYP1A2 2856/4885CYP2D6 3373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.