Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4433377 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HTTCYP2C19 | |
| SCHEMBL14087704 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HTTCYP2C19 | |
| SCHEMBL4421913 | 0.80 | POLB (0.57) | ALDH1A1HTT | |
| SCHEMBL10025783 | 0.73 | ALDH1A1 (0.90) | ALDH1A1 | |
| SCHEMBL4423510 | 0.68 | ALDH1A1 (0.47) | ALDH1A1HTTCYP2C19 | |
| SCHEMBL4423861 | 0.68 | POLB (0.51) | — | |
| SCHEMBL10025798 | 0.67 | ALDH1A1 (1.00) | ALDH1A1 | |
| SCHEMBL4433327 | 0.65 | POLB (0.53) | — | |
| SCHEMBL5043832 | 0.65 | ALDH1A1 (0.41) | ALDH1A1HTT | |
| SCHEMBL8283793 | 0.64 | ALDH1A1 (0.59) | ALDH1A1HTTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723116-B1 | TETRAHYDROQUINOLINONES AND THEIR USE AS ANTAGONISTS OF METABOTROPIC GLUTAMATE RECEPTORS | MERZ PHARMA GMBH & CO KGAA (DE) | 2008-09-24 | — | — | EP | disclosed |