Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088416 | 0.96 | THRB (0.51) | THRBTSHRHPGDCNR1CNR2 | |
| SCHEMBL14088415 | 0.93 | TSHR (0.49) | THRBTSHRHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL14088419 | 0.88 | THRB (0.47) | THRBTSHRHPGDCNR1CNR2 | |
| SCHEMBL14088417 | 0.88 | THRB (0.44) | THRBTSHRHPGDLMNAL3MBTL1 | |
| SCHEMBL14088460 | 0.87 | THRB (0.48) | THRBTSHRHPGDLMNAL3MBTL1 | |
| SCHEMBL14088446 | 0.87 | THRB (0.46) | THRBTSHRHPGDCNR1CNR2 | |
| SCHEMBL14088413 | 0.86 | TSHR (0.42) | TSHRHPGDL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL14088451 | 0.85 | THRB (0.48) | THRBTSHRHPGDLMNAALDH1A1 | |
| SCHEMBL14088462 | 0.84 | THRB (0.49) | THRBTSHRHPGDLMNAL3MBTL1 | |
| SCHEMBL14088439 | 0.84 | THRB (0.47) | THRBTSHRHPGDCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410677-B2 | Organosilicon compound-containing polymerizable liquid-crystal composition | CHISSO CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |