Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088580 | 0.88 | THRB (0.48) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL14088510 | 0.88 | TSHR (0.44) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL14088581 | 0.87 | THRB (0.47) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL14588353 | 0.86 | THRB (0.46) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL14088587 | 0.86 | TSHR (0.39) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL13123109 | 0.86 | THRB (0.43) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL14088578 | 0.85 | THRB (0.45) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL13107451 | 0.85 | HTT (0.43) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL13107466 | 0.85 | THRB (0.42) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL13107458 | 0.84 | TSHR (0.40) | TSHRALDH1A1CYP3A4THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410677-B2 | Organosilicon compound-containing polymerizable liquid-crystal composition | CHISSO CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |
| US-7410677-B2 | Organosilicon compound-containing polymerizable liquid-crystal composition | CHISSO CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |
| US-7157124-B2 | Polymerizable compounds and their polymers | CHISSO PETROCHEMICAL CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157124-B2 | Polymerizable compounds and their polymers | CHISSO PETROCHEMICAL CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |