Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088556 | 0.96 | THRB (0.52) | THRBPPARGPPARDFFAR1TSHR | |
| SCHEMBL22451265 | 0.90 | THRB (0.64) | THRBPPARGPPARDFFAR1TSHR | |
| SCHEMBL17036974 | 0.86 | THRB (0.62) | THRBPPARGPPARDFFAR1TSHR | |
| SCHEMBL8031169 | 0.86 | THRB (0.62) | THRBPPARGPPARDFFAR1TSHR | |
| SCHEMBL17791310 | 0.86 | THRB (0.62) | THRBPPARGPPARDFFAR1TSHR | |
| SCHEMBL14329709 | 0.85 | THRB (0.57) | THRBPPARGPPARDFFAR1TSHR | |
| SCHEMBL10046612 | 0.84 | THRB (0.68) | THRBPPARGPPARDTSHRHPGD | |
| SCHEMBL8044896 | 0.83 | THRB (0.59) | THRBPPARGPPARDTSHRHPGD | |
| SCHEMBL12733650 | 0.83 | THRB (0.55) | THRBPPARGPPARDTSHRHPGD | |
| SCHEMBL19215898 | 0.83 | THRB (0.49) | THRBPPARGPPARDFFAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410677-B2 | Organosilicon compound-containing polymerizable liquid-crystal composition | CHISSO CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |