Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088560 | 0.96 | POLB (0.52) | LMNANPC1POLBCYP1A2CYP2C9 | |
| SCHEMBL21413224 | 0.93 | HTT (0.58) | LMNANPC1POLBCYP1A2CYP2C9 | |
| SCHEMBL21413226 | 0.90 | LMNA (0.44) | LMNANPC1POLBCYP1A2CYP2C9 | |
| SCHEMBL14088561 | 0.87 | POLB (0.41) | LMNANPC1POLBCYP1A2CYP2C9 | |
| SCHEMBL16746159 | 0.86 | KMT2A (0.40) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21413223 | 0.84 | HTT (0.67) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL14088567 | 0.83 | POLB (0.41) | LMNANPC1POLBCYP1A2CYP2C9 | |
| SCHEMBL14088566 | 0.83 | HTT (0.46) | LMNANPC1POLBCYP1A2CYP2C9 | |
| SCHEMBL14088599 | 0.83 | HTT (0.45) | LMNANPC1POLBCYP1A2CYP2C9 | |
| SCHEMBL11961765 | 0.82 | POLB (0.68) | LMNANPC1POLBCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410677-B2 | Organosilicon compound-containing polymerizable liquid-crystal composition | CHISSO CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |