⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408903 | 1.00 | — | — | |
| SCHEMBL21297030 | 0.85 | — | — | |
| SCHEMBL21297029 | 0.85 | — | — | |
| SCHEMBL13822405 | 0.82 | — | — | |
| SCHEMBL13822403 | 0.82 | — | — | |
| SCHEMBL18320740 | 0.82 | — | — | |
| SCHEMBL728877 | 0.77 | — | — | |
| SCHEMBL728876 | 0.77 | — | — | |
| SCHEMBL11146048 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL11146045 | 0.77 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294101-B1 | POLYMERS MODIFIED BY SILANES | DOW SILICONES CORP (US) | 2018-10-17 | — | — | EP | disclosed |
| US-8476375-B2 | Polymers modified by silanes | DOW CORNING CORPORATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110178198-A1 | POLYMERS MODIFIED BY SILANES | DOW SILICONES CORPORATION | 2011-07-21 | — | — | US | disclosed |
| EP-2294101-A1 | POLYMERS MODIFIED BY SILANES | Dow Corning Corporation (US) | 2011-03-16 | — | — | EP | disclosed |
| WO-2010000479-A1 | POLYMERS MODIFIED BY SILANES | DOW CORNING CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |