SCHEMBL14090771

SCHEMBL14090771

CO[Si](CCCNC(=O)NCCOP(=O)(O)O)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 3/20 0.41
LPAR2 Q9HBW0 3/20 0.41
ENPP2 Q13822 1/20 0.41
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
LPAR3 Q9UBY5 3/20 0.36
S1PR2 O95136 2/20 0.35
S1PR1 P21453 2/20 0.35
S1PR3 Q99500 2/20 0.35
S1PR5 Q9H228 1/20 0.35
EPHX1 P07099 4/20 0.34
TSHR P16473 1/20 0.34
EPHX2 P34913 1/20 0.34
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL254189 0.83 EPHX1 (0.46) EPHX1TSHREPHX2POLBTDP1
SCHEMBL13950680 0.82 TSHR (0.52) EPHX1TSHREPHX2POLBTDP1
SCHEMBL14090770 0.81 EPHX1 (0.36) CA12CA1CA2CA9EPHX1
SCHEMBL16804329 0.79 LPAR3 (0.50) LPAR1LPAR2ENPP2LPAR3
SCHEMBL16986431 0.79 EPHX2 (0.43) EPHX1TSHREPHX2POLBTDP1
SCHEMBL9280834 0.79 EPHX2 (0.43) EPHX1TSHREPHX2POLBTDP1
SCHEMBL30784617 0.79 EPHX1 (0.37) EPHX1TSHREPHX2POLBTDP1
SCHEMBL19838191 0.77 EPHX1 (0.50) EPHX1EPHX2
SCHEMBL10557593 0.76 EPHX1 (0.57) EPHX1EPHX2
SCHEMBL28427817 0.76 EPHX1 (0.45) EPHX1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207849-A1 HYDROPHILIC FILM FORMING COMPOSITION AND HYDROPHILIC MEMBER FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed