SCHEMBL254189

SCHEMBL254189

CO[Si](CCCNC(=O)NCCC[Si](OC)(OC)OC)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 7/20 0.46
PRMT1 Q99873 1/20 0.40
EPHX2 P34913 3/20 0.38
TSHR P16473 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPK1 P28482 1/20 0.36
HIF1A Q16665 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
POLB P06746 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19838191 0.93 EPHX1 (0.50) EPHX1PRMT1EPHX2KDM4EMAPK1
SCHEMBL28427817 0.92 EPHX1 (0.45) EPHX1EPHX2
SCHEMBL10557593 0.92 EPHX1 (0.57) EPHX1EPHX2MEN1KMT2A
SCHEMBL13907618 0.92 EPHX1 (0.59) EPHX1EPHX2NPC1RAB9A
SCHEMBL18372170 0.90 EPHX1 (0.39) EPHX1PRMT1EPHX2TSHR
SCHEMBL14865799 0.90 EPHX1 (0.39) EPHX1PRMT1EPHX2TSHRNPC1
SCHEMBL13950680 0.90 TSHR (0.52) EPHX1EPHX2TSHRKDM4EPOLB
SCHEMBL12190470 0.90 EPHX1 (0.39) EPHX1PRMT1EPHX2TSHRPOLB
SCHEMBL14519143 0.90 EPHX1 (0.39) EPHX1PRMT1EPHX2TSHRNPC1
SCHEMBL754945 0.90 KEAP1 (0.43) EPHX1EPHX2TSHRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680687-A1 SOFT POLYSILOXANE CORE-SHELL ABRASIVES FOR CHEMICAL MECHANICAL PLANARIZATION Versum Materials US, LLC (US) 2026-01-21 EP claimed
WO-2025122886-A1 SYSTEMS FOR SUPERELASTIC SPLINES WITH POLYMER INSULATION ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. (US) 2025-06-12 WO claimed
WO-2025111296-A1 ELECTROLYTE COMPOSITIONS AND ELECTROCHEMICAL DEVICES USING THE SAME II-VI DELAWARE, INC. (US) 2025-05-30 WO claimed
WO-2024191746-A1 SOFT POLYSILOXANE CORE-SHELL ABRASIVES FOR CHEMICAL MECHANICAL PLANARIZATION VERSUM MATERIALS US, LLC (US) 2024-09-19 WO claimed
WO-2022261559-A9 ANTIFOULING MATERIALS, COMPOSITIONS AND METHODS OF USE ACatechol, Inc. (US) 2023-11-30 WO claimed
US-11629235-B2 Urea-functionalized sol-gel KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-04-18 US claimed
CN-110191701-B Composition for enhancing protein strength 株式会社LG生活健康 2023-02-21 CN claimed
WO-2022261559-A2 ANTIFOULING MATERIALS, COMPOSITIONS AND METHODS OF USE ACatechol, Inc. (US) 2022-12-15 WO claimed
EP-3661997-B1 MOISTURE CURABLE COMPOSITIONS DOW SILICONES CORP (US) 2022-11-09 EP claimed
EP-3661996-B1 MOISTURE CURABLE COMPOSITIONS DOW SILICONES CORP (US) 2022-07-20 EP claimed
WO-2019024430-A1 MOISTURE CURABLE COMPOSITIONS DOW SILICONES CORPORATION (US) 2019-02-07 WO claimed
US-8609755-B2 Storage stable composition of partial and/or complete condensate of hydrolyzable organofunctional silane MOMENTIVE PERFOMANCE MATERIALS INC. (US) 2013-12-17 US claimed
US-8372515-B2 Silane coating compositions containing silicon-based polyether copolymers, methods for coating metal surfaces and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-02-12 US claimed
US-20100178521-A1 SILANE COATING COMPOSITIONS CONTAINING SILICON-BASED POLYETHER COPOLYMERS, METHODS FOR COATING METAL SURFACES AND ARTICLESMADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-07-15 US claimed
US-20080268162-A1 Method of applying an anti-corrosion and/or adhesion promoting coating to a metal and resulting coated metal MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-30 US claimed
EP-1242540-B1 USE OF FLUID RESISTANT SILICONE COMPOSITIONS FOR SEALING MAGNESIUM ALLOY COMPONENTS HENKEL CORP (US) 2007-04-04 EP claimed
US-6645339-B1 Fluid resistant silicone compositions for sealing magnesium alloy components HENKEL LOCTITE CORPORATION 2003-11-11 US claimed
EP-0304701-B1 Polyalkoxysilyl-terminated polydiorganosiloxanes, methods for their preparation, and room temperature vulcanizable compositions containing them GEN ELECTRIC (US) 1994-12-07 EP claimed
US-4863992-A Polyalkoxysilyl-terminated polydiorganosiloxanes, methods for their preparation, and room temperature vulcanizable compositions containing them GENERAL ELECTRIC COMPANY (US) 1989-09-05 US claimed
EP-0304701-A2 Polyalkoxysilyl-terminated polydiorganosiloxanes, methods for their preparation, and room temperature vulcanizable compositions containing them GENERAL ELECTRIC COMPANY (US) 1989-03-01 EP claimed