Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010176 | 0.79 | NQO1 (0.39) | CYP2A6KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL13726356 | 0.74 | JAK2 (0.33) | CYP2A6MEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL12761337 | 0.74 | JAK2 (0.33) | CYP2A6MEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL5011038 | 0.72 | — | — | |
| SCHEMBL12743233 | 0.69 | MEN1 (0.39) | CYP2A6MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9248443 | 0.69 | PTGDR2 (0.46) | CYP2A6KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL30874683 | 0.69 | PTGDR2 (0.46) | CYP2A6KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL31261448 | 0.69 | PTGDR2 (0.36) | CYP2A6KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL12761336 | 0.69 | CYP2A6 (0.47) | CYP2A6KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL264003 | 0.69 | CYP2A6 (0.50) | CYP2A6KDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |