Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377784 | 0.79 | NQO1 (0.36) | NQO1ALDH1A1TDP1TSHRHSD17B10 | |
| SCHEMBL14092890 | 0.79 | CYP2A6 (0.41) | ALDH1A1CYP2A6MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL3420318 | 0.78 | ALDH1A1 (0.40) | NQO1ALDH1A1TDP1TSHRHSD17B10 | |
| SCHEMBL354097 | 0.77 | ALDH1A1 (0.42) | NQO1ALDH1A1TDP1TSHRHSD17B10 | |
| SCHEMBL27686228 | 0.76 | ALDH1A1 (0.39) | NQO1ALDH1A1TDP1TSHRHSD17B10 | |
| SCHEMBL354096 | 0.76 | ALDH1A1 (0.39) | NQO1ALDH1A1TDP1TSHRHSD17B10 | |
| SCHEMBL9651812 | 0.75 | CA2 (0.41) | ALDH1A1TDP1TSHRCA2MAPT | |
| SCHEMBL22411205 | 0.75 | NQO1 (0.33) | NQO1ALDH1A1TDP1TSHRHSD17B10 | |
| SCHEMBL24859351 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRHSD17B10HIF1A | |
| SCHEMBL4599393 | 0.74 | CA2 (0.43) | NQO1ALDH1A1TDP1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |